PRINCIPLE: a tool for associating genes with diseases via network propagation
نویسندگان
چکیده
SUMMARY PRINCIPLE is a Java application implemented as a Cytoscape plug-in, based on a previously published algorithm, PRINCE. Given a query disease, it prioritizes disease-related genes based on their closeness in a protein-protein interaction network to genes causing phenotypically similar disorders to the query disease. AVAILABILITY Implemented in Java, PRINCIPLE runs over Cytoscape 2.7 or newer versions. Binaries, default input files and documentation are freely available at http://www.cs.tau.ac.il/~bnet/software/PrincePlugin/. CONTACT [email protected]; [email protected].
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عنوان ژورنال:
- Bioinformatics
دوره 27 23 شماره
صفحات -
تاریخ انتشار 2011